In this webinar on May 27th, we will explore how signal peptide engineering is emerging as a powerful strategy to improve mRNA therapeutics.
January 12, 2026
Avenue Biosciences raises $5.7M to scale the first platform modulating the secretory pathway for enhanced therapeutic protein manufacturing
June 11, 2025
Avenue Biosciences Selected for 2025 BioTools Innovator Accelerator Program
May 20, 2025
Veli-Pekka Jaakola joins Avenue Biosciences as Chief Technology Officer
October 22, 2024
Avenue Biosciences Raises $2.5M Seed to Scale AI-Enhanced Protein Engineering
October 7, 2024
Avenue Biosciences Welcomes Industry Experts to Advisory Board for Market Insights and Focused Growth
October 4, 2024
Avenue Biosciences Joins StartX, the Largest Community of Stanford Founders
Synthetic signal peptides and why they matter in developing protein-based therapies
Computational models are emerging as a new way to design and optimize protein-based therapies. Here’s how this emerging field is already changing discovery and manufacturability.
Unlocking mRNA Performance: Signal Peptide Engineering for Next-Generation Therapeutics
In this webinar on May 27th, we will explore how signal peptide engineering is emerging as a powerful strategy to improve mRNA therapeutics.
Signal peptides in biosimilar development: Small sequences, big impact
With over 200 biosimilars approved globally (1) and many top-selling biologics losing exclusivity in the next five years, the demand for cost-efficient, large-scale production of recombinant antibody therapeutics is growing.
Reviewing real-life success stories: How signal peptide engineering can boost mRNA therapy development
Strong evidence exists for applying signal peptide engineering to design more efficient vaccines for various infectious viral diseases, including Ebola virus, SARS-Cov-2, and Zika virus.
The virus innovates – why aren’t we? Rethinking signal peptides in biologics development
While viruses tirelessly reinvent themselves to optimize infection and immune evasion, including refining their signal peptides to optimize viral replication in the secretory pathway, the ability to engineer viral signal peptides for biotechnology tends to remain limited.
Understanding signal peptides: Small expression elements and their therapeutic implications
This blog sheds light on the significant role of signal peptides in protein synthesis and therapy development.