In this blog, we examine how signal peptide engineering can address challenges in the expression of de novo-designed proteins.
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Using signal peptides to enhance expression of de novo-designed proteins
In this blog, we examine how signal peptide engineering can address challenges in the expression of de novo-designed proteins.
Leveraging signal peptides for smarter mRNA design
Advances in high throughput signal peptide analysis and computational models are creating new possibilities for smarter mRNA design.
Signal peptides – a significantly underutilized element in protein engineering
Despite existing in hundreds of thousands and expressing significant diversity, signal peptides have largely remained unexplored in commercial protein engineering. This is a missed opportunity as almost all therapeutic proteins and mRNA therapies contain a signal peptide that can be engineered for optimized production and functionality.
Meet us at PEGS Europe 2024
PEGS Europe, a biologics technology conference will be held in Barcelona, on November 5-7. Join our talk on November 6 by CEO Tero-Pekka Alastalo on optimizing protein expression with signal peptides.