Webinar

Webinar: Optimizing the Secretory Pathway – High-Throughput Protein Engineering for Therapeutic Manufacturing

February 6, 2026
Webinar

Webinar: Optimizing the Secretory Pathway – High-Throughput Protein Engineering for Therapeutic Manufacturing

February 6, 2026

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About

Time: March 3, 11 am EST
Presenter: CEO Tero-Pekka Alastalo (MD, PhD)

Maximizing protein yield and minimizing production cost iscrucial to achieve commercial viability and broad patient access.

A major engineering opportunity is the cell’s secretory pathway, which governs protein folding, post-translational modification, and export. Although most biologics depend on this pathway, it remains one of the least predictable and least engineered stages of bioprocessing.

This webinar covers:

  • Why the secretory pathway is a dominant but under-engineered constraint on protein yield in mammalian expression systems.
  • How signal peptides function as modulators to the secretory pathway and can have significant effects on protein yield and quality.
  • Evaluate technological advances that enable creating thousands of variations of the target of interest.
  • Identify practical opportunities to applying secretion optimization strategies across antibodies, vaccines, and novel modalities without altering the final therapeutic target.
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