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Unlocking mRNA Performance: Signal Peptide Engineering for Next-Generation Therapeutics

In this webinar on May 27th, we will explore how signal peptide engineering is emerging as a powerful strategy to improve mRNA therapeutics.

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Unlocking mRNA Performance: Signal Peptide Engineering for Next-Generation Therapeutics

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Blog post
Published on 
April 8, 2025
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Abstract of AI designed proteins

Using signal peptides to enhance expression of de novo-designed proteins

In this blog, we examine how signal peptide engineering can address challenges in the expression of de novo-designed proteins.

Using signal peptides to enhance expression of de novo-designed proteins
Blog post
Published on 
December 18, 2024
By 
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abstract futuristic elements

Leveraging signal peptides for smarter mRNA design

Advances in high throughput signal peptide analysis and computational models are creating new possibilities for smarter mRNA design. 

Leveraging signal peptides for smarter mRNA design
Blog post
Published on 
October 16, 2024
By 
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Signal peptides – a significantly underutilized element in protein engineering

Despite existing in hundreds of thousands and expressing significant diversity, signal peptides have largely remained unexplored in commercial protein engineering. This is a missed opportunity as almost all therapeutic proteins and mRNA therapies contain a signal peptide that can be engineered for optimized production and functionality.

Signal peptides – a significantly underutilized element in protein engineering
Events
Published on 
October 7, 2024
By 
Avenue Biosciences Team
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Avenue Biosciences attending PEGS

Meet us at PEGS Europe 2024

PEGS Europe, a biologics technology conference will be held in Barcelona, on November 5-7. Join our talk on November 6 by CEO Tero-Pekka Alastalo on optimizing protein expression with signal peptides.

Meet us at PEGS Europe 2024